[Bug 47949] New: .NET 4.x and later do not run on MacOS with 64 bit prefix

[WineHQ Bugzilla]

https://bugs.winehq.org/show_bug.cgi?id=47949

Bug ID: 47949
           Summary: .NET 4.x and later do not run on MacOS with 64 bit
                    prefix
           Product: Wine
           Version: 4.17
          Hardware: x86-64
                OS: Mac OS X
            Status: UNCONFIRMED
          Severity: major
          Priority: P2
         Component: -unknown
          Assignee: [e-mail]
          Reporter: [e-mail]

No matter the release version, I have not seen a .NET 4.x implementation
running on Mac OS in a win64 prefix.

After many attempts, all paths of installing, upgrading, repairing, etc. end
with:

Application: 64-console4.exe\nFramework Version: v4.0.30319\nDescription: The
process was terminated due to an internal error in the .NET Runtime at IP
000006447F1D6F19 (000006447F100000) with exit code 80131506.\n"

That memory address is the clr.dll itself.

Is anyone aware of any users ever getting MacOS + win64 + .NET 4.x or later
working with wine?