http://bugs.winehq.org/show_bug.cgi?id=25600
--- Comment #5 from Dmitry Timoshkov dmitry@baikal.ru 2012-02-03 00:05:13 CST --- (In reply to comment #4)
Backtrace: =>0 0x00587314 in skype (+0x187314) (0x00000000) 0x00587314: int $0x2e
This is a direct NT syscall, this can't work in Wine.