https://bugs.winehq.org/show_bug.cgi?id=42769
--- Comment #11 from David Girón duhowpi@gmail.com --- (In reply to Alistair Leslie-Hughes from comment #10)
(In reply to Jeff Bigler from comment #7)
Created attachment 57954 [details] Warframe freezing with a deadlock
The previous file turned out to only contain Warframe logs, no Wine logs. So I am replacing it with another log of a frozen game that contains the complete data.
The game often also will completely crash with GPF errors on occasion, before it has a chance to freeze, but that is likely a different bug.
The log has wined3d-csmt.dll, try disabling this dll in winecfg and try again.
Disabling it makes the game visually glitched (breaks/opens map, sometimes enemies and main character invisible), and still crashes.