http://bugs.winehq.org/show_bug.cgi?id=31201
--- Comment #5 from Dan Kegel dank@kegel.com 2012-07-12 13:58:27 CDT --- Rolled back to wine-1.5.8 and was able to run mclicense.exe again. The patch changed to error dialog to "Error: PTC.Setup could no properly detect the Host ID that is required."
http://www.ptc.com/for/education/tryout_faq.htm#12 makes it sound like they do consider the MAC address the Host ID.
See attached log.