http://bugs.winehq.org/show_bug.cgi?id=24816
--- Comment #9 from Dan Kegel dank@kegel.com 2011-02-04 18:05:28 CST --- Try starting with an empty .wine directory, e.g. cd $HOME mv .wine .wine.old Then run the installer.
But "wine start WebPlus X2:/setup.exe" is kind of a freaky command. Is "WebPlus X2:" a directory, or what?