http://bugs.winehq.org/show_bug.cgi?id=27382
--- Comment #17 from Huw Davies huw@codeweavers.com 2011-10-10 07:20:01 CDT --- (In reply to comment #16)
This sounds like it is better explained by Bug 28369 where I also experienced this bug somewhat randomly. The commit in comment #8 also seems unrelated and the problem probably isn't related to file system at all, hence the aforementioned bug.
...which has been reported fixed. Please retest.