https://bugs.winehq.org/show_bug.cgi?id=42330
--- Comment #28 from BieHDC byi5000@gmail.com --- Alt-Entering still works with newest GTA 5 and wine-2.11-staging, but it got harder to achieve the rendering. I usually need 3 tries to get it work and i do it by spamming alt-enter as soon as i hear the sound. If it doesnt render after spamming for about 2 minutes, kill the gta process and retry (i have a terminal open with the "wine taskmgr" command and just open the wine taskmanager, scroll with the arrow keys to the process and press ALT+B(german keyboard) to end the process)
Yes its a bit painful and i hope this issue gets fixed soon, but you can still play the game, you just need to try harder