http://bugs.winehq.org/show_bug.cgi?id=31341
--- Comment #1 from Bruno Jesus 00cpxxx@gmail.com 2012-07-28 07:55:34 CDT --- Do you mean the keyboard stops working for every other linux application or just wine programs? Did you try winecfg for example?
Do you have anything else installed in the same game prefix? Try wineserver -k for the game prefix before launching it again and see if that helps.