http://bugs.winehq.org/show_bug.cgi?id=6297
--- Comment #20 from Phil Costin philcostin@hotmail.com 2007-10-18 16:36:25 --- The way I have been getting around this for the last few months is hitting Alt+F2 in KDE and typing sync at exactly the right point to flush the disk cache. It's a little hit and miss but it seems to greatly improve the chance of getting the game to start.
I've now got the feel for doing it at almost exactly the right moment, which is about a second and a half before you feel the cancel button is about to grey out on the "preparing to launch" window.