http://bugs.winehq.org/show_bug.cgi?id=6971
--- Comment #502 from Erich Hoover ehoover@mines.edu 2011-05-14 12:50:53 CDT --- (In reply to comment #501)
The 360 degree mouse rotation in Wine 1.3.20 on Mass Effect 2 works completly.
I'm not sure if there's a way to "unlink" an application from a bug, but this issue is also fixed with Fallout 3 in Wine 1.3.20.