http://bugs.winehq.org/show_bug.cgi?id=8033
--- Comment #63 from Austin English austinenglish@gmail.com 2007-10-10 16:33:53 --- Running wineprefixcreate won't necessarily update any changed registry entries, but it will add any _new_ entries that weren't there previously. Again, this is why it is encouraged to test with a clean .wine directory each time to eliminate the registry as a cause of the error. Even though wineprefixcreate will update your registry correctly most of the time, there are still times when it won't (such as you reported). Again, this is something that will have to be addressed by the time wine 1.0 comes out, but until this, this is still very much an alpha project.