http://bugs.winehq.org/show_bug.cgi?id=6971
--- Comment #445 from Brian Vuyk brian@brianvuyk.com 2011-03-14 11:29:42 CDT --- (In reply to comment #442)
The problem only arises, I guess, when the application thinks it's full screen but is being run in a virtual desktop.
This is also the case when you are using two monitors with Nvidia's TwinView mode turned on. This gives you a desktop resolution of (in my case) 3200x1080. With a fullscreen game on one monitor running at 1920x1080, the mouse will stray into my other desktop screen and clicks will change focus onto other items running on that desktop.
The solution in this case is to only run on a single monitor for now, but I agree, if a fullscreen app has focus, the mouse should not be able to leave that window.