http://bugs.winehq.org/show_bug.cgi?id=8291
--- Comment #11 from Brian Vuyk brian@brianvuyk.com 2008-01-15 07:16:52 --- Please note that the mouse centering bug does not appear in the menus if compatibility is changed to Windows XP. However, in that case, the mouse sticks towards the center of the screen when the player is actually 'in-game' and not in the menu system.
Other compatibilities, the mouse sticks to the center of the screen in the menu system, and you can't even get to the in-game system since you can't escape the menus.