http://bugs.winehq.org/show_bug.cgi?id=5615
--- Comment #6 from Austin English austinenglish@gmail.com 2009-01-27 13:45:08 --- (In reply to comment #5)
what I did was: started AutoRun.exe with Nautilus, closed Nautilus after that! I could not eject with cd-rom drive button however eject with "wine eject d:" in terminal worked like a charme
Perhaps gnome still had it open somewhere? What does lsof say?