There are quite a few things that cause the app to crash or draw windows in a funny way. Once the app is slighlty useable, I can list more bugs.
Yeah, I just tried it. Clearly not happy at all. I'm getting lots of errors saying it didn't call BeginPaint in a WM_PAINT handler, which iirc is a bug in the app? I think you're always supposed to call BeginPaint when you receive a WM_PAINT message at some point (unless it's actually a bug in the wine controls library).
It doesn't run at all with the latest version of CrossOver, with the Dec 19th release it runs but with lots of nasty bugs. I don't see the menu duplication error though.
When I got that automated email from Synergy I replied telling them about Wine, maybe they'd be willing to help it run. Oh well, here's to dreaming :)
BTW I am very much a newbie Wine developer so I can probably give hints only.