Hrm. Haven't seen this one before. At the end of installation of IBM Homepage Builder 6.0 for Windows, I get
wine: cannot open builtin library for L"C:\windows\system32\regsvr32.exe": /home/dank/wine/programs/regsvr32.exe.so: invalid ELF header
This is with 0.9.3 built on fc3.
Thanks, Dan -- Wine for Windows ISVs: http://kegel.com/wine/isv