Not that I mean to sound like a pessimist, but I'm really just calling it as I see it. No offense to anyone intended. :)
This, in a nutshell, is Wine's greatest challenge (stepping even outside ISV boundaries for a minute).
I believe, either because I'm insane (the likely explanation), or because it's true, that Wine has progressed remarkably in the past 5 years, and can no longer be correctly dismissed as unstable or unusable.
I think the shift from Alpha to Beta status was a more dramatic signal that anyone really realizes; I think it marks the point where Wine can reliably be used for a broad range of purposes.
But, bluntly, we have to prove it. We have to start by continuing the drive to a solid 1.0; we have to continue helping a small number of ISVs really succeed.
And then of course comes the fun part; we have to hold that line and not let any regressions in :-/.
But I think we can do it; it's why I'm still here.
Someday I hope to stop apologizing for Wine (and for Linux for that matter) and start bragging; and I don't think that day is too far ahead (it better not be, my wife is really getting mad at me :-/).
Sorry, I'd type more, but these friendly men tell me they have a nice white jacket they want me to try on...
Cheers,
Jeremy