Hi, Axel.
Don't be afraid of trying different solutions - you can (and should) always backup your wine prefix (just copy your entire ~/.wine directory somewhere). Then you can experiment safely and copy your backup over ~/.wine back if anything goes wrong.
And just a little off-topic remark - you should not send emails to so many email addresses. wine-devel@winehq.org alone is more than enough - all interested parties are reading it. More than that, your topic probably belongs to wine-users, not wine-devel. But that's my personal opinion. If you want to be absolutely sure that one particular user will read your message - add his/her email to CC. No need to send to wine-releases, wine-tests-results, wine-bugs and wineconf.