glibc versions

Are there any issues with more recent glibc?

I am looking to what has changed on my system since I had wine working  
nicely a few months back.

It occured to me that I probably have updated glibc at some point possibly  
later then the wine build that worked to well until I foolishly tried to  
update it.

Is there anything here we need to be aware of?

TIA for any detail.

Regareds