Trading off configurability with usability seems fine to me.
We aren't as one can tweak things with winecfg if he wants/needs to
The goal is to solve both the lack of config files for binary installs, fixed by the patches that Che has in his rpm package and Marcus has for Suse, and for users that run 'make install' but never create config files.
All this can be solved by shipping a config file with with wine, get wine to adapt it to the users system, install it, install the registry and create the fake windows partition. This would work for all binaries on all distros, even on freebsd, and would work when installing from source. Only that someone has to implement it. And volunteers?