Hello,
I modified the existing Homebrew formular for Wine in order to make shared WoW64 (32bit and 64bit Wine together) possible: https://github.com/kaazoo/homebrew/commit/cd0f1db42e0a8228740fce347604d1cfe3...
The changes are not yet upstream, so you'll need to overwrite /usr/local/Library/Formula/wine.rb with my version.
The upcoming LLVM 3.8 release is a dependency for the 64bit build:
brew install llvm --with-clang --with-clang-extra-tools --with-compiler-rt --with-libcxx --with-lld --with-rtti --HEAD
After that Wine 1.9.0 can be installed via:
brew install wine --with-win64 --without-x11 --devel
Regards, kaazoo